Association of adenovirus type 2 with encephalitis: A new case report

Association of adenovirus type 2 with encephalitis

Abstract

Adenovirus is a common respiratory pathogen in children that sometime produces encephalitis symptoms in affected children. Very few reports are available on association of adenovirus type 2 with encephalitis cases. However, none of the cases have been reported from India. We have detected and characterized the adenovirus from the clinical specimens collected from a six year old boy who had the symptoms of encephalitis.
The adenovirus was isolated from all the three specimens; CSF, serum and throat swab in HEK-293 cells. The presence of adenovirus was confirmed by PCR. Sequencing and BLAST search analysis confirmed that the isolated adenovirus belonged to adenovirus type 2. As per our knowledge this is the first report of adenovirus type 2 associated with encephalitis case from India.