Autopsy Study of Heart with special emphasis on coronary artery lesions

Abstract

Aims and objectives: Establishments of relation between various patients’ factors (age, sex) with various histo-pathological pattern of hearts as well as analyse the histomorphological pattern of Coronary artery lesions in Heart. Materials and Method: The heart with the aorta was removed from the body and studied in detail. The heart was examined externally to note the size, weight, fat deposition, course of coronary arteries, thickening of coronaries, scars etc. Gross examination of the walls for the presence of Infarct, the thickness of the ventricular walls and inter-ventricular septum were recorded. The aorta, right and left coronary arteries were examined for atherosclerosis, aneurysmal dilatation and congenital abnormalities. Tissue bits were taken for microscopic study from both ventricles, representative sections from right coronary artery, left anterior descending artery and left circumflex branch of left coronary artery, from inter-ventricular septum, apex and from aorta. Results & Conclusion: In the present study, the atherosclerosis of coronary artery disease was the most frequently encountered lesion contributing to death. Males were affected more frequently than the females by atherosclerotic coronary artery disease. Left anterior descending branch of left coronary artery is the most commonly involved in atherosclerosis. In cases of Ischaemic Heart Disease triple vessel disease was found predominantly.