A study of Bone marrow aspirations and examination as a diagnostic tool in Hematological disorders

Abstract

In the present study 75 cases of blood disorders and bone marrow disorders occurring in pediatric patients, at the Guru Gobind Singh Hospital, were studied in, Department of Pathology, Shri M. P. Shah Medical College, Jamnagar from the year December 2001 to December 2003. Most numbers of patients were diagnosed with megaloblastic anaemia of these 63.6% were males and 36.3% were female patients. And majority of patients were in the age group of 1 month to 2 years of age in case of megaloblastic anaemia. The most common presenting symptom was fever, followed incidence by pallor and bleeding tendencies. The second most common abnormality detected in bone marrow smears of children was erythroid hyperplasia of varying degrees and it was followed in incidence by Gaucher's disease and dimorphic anaemia. In case of Gaucher's disease 60% were female and 40% were male patients and the common age of presentation of all these patients were in the age group of 1 year to YA years. Most common presenting symptom was found to be pallor and it was associated with hepatospelenomegaly.