Sheehan’s Syndrome Presenting with Double Depression- A Diagnostic Challenge

Abstract

Endocrine disorders are common medical conditions. As hormones affect a variety of organ systems, endocrinopathies may produce a variety of psychiatric symptoms. Early in the course of endocrine disease patients are more likely to present primarily with psychiatric symptoms. Here we are presenting a case with persistent low mood and decreased interest for a period of two and half years with frequent episodes of weakness, laziness, tiredness, giddiness, disturbed sleep, tremulousness while walking, inability to walk without support, decrease food intake and occasional vomiting with increased worry, decreased personal care, social interaction and no interest in any activity lasting for 10 to 20 days.
She was treated successfully every time with antidepressants and Anxiolytic along with intravenous fluid. Considering the recurrent nature of the illness, it was a diagnostic and therapeutic challenge for the treating psychiatrists. Later on the case was diagnosed to have Sheehan’s syndrome- hypopituitarism, with double depression and treatment with only hormone replacement therapy showed significant improvement in terms of depressive and other symptoms