Non-Ketotic Hyperglycemia Induced Chorea (NKHIC): A Case Report and review of literature

Ketotic Hyperglycemia Induced Chorea (NKHIC): A Case Report and review of literature

Abstract

Case report: we report a 68-year-old woman known diabetic patient who presented with
uncontrolled involuntary movement of left half of body associated with non-ketotic
hyperglycemia and respond to treatment of hyperglycemia.
Methods: A retrospective review of clinical, radiological and laboratory findings in a patient
with chorea associated with non-ketotic hyperglycemia.
Results: we report a patients presented with acute hemichorea, with a history of long standing
diabetes mellitus and uncontrolled diabetes mellitus. The initial cranial CT scans revealed hyper
density bilateral putamen and caudate nuclei more marked on right side contra-lateral to the side
of chorea. Her laboratory investigation showed a non-Ketotic hyperglycemia and, hence,
hyperglycemia-induced hemi-chorea diagnosis was made. Chorea partially responded to
treatment for hyperglycemia and patient also treated with tetrabenzine.
Conclusion: Hemi-chorea associated with diabetic non-Ketotic hyperglycemia may present with
acute neurologic manifestation resemble stroke. Diagnosis of this clinical and radiological
condition is important because treatment of the underlying hyperglycemia will lead to correction
of chorea.