Morphological Spectrum Of Vesiculobullous Skin Lesions Attending Tertiary Care Centre

Morphological Spectrum Of Vesiculobullous Skin Lesions

Abstract

Background: Vesiculobullous disorders represent a heterogeneous group of dermatoses with protean manifestations usually associated with fluid filled skin lesions. They usually occur as a part of the spectrum of various infectious, drug-induced, genetic, inflammatory and autoimmune disorders. Material And Methods: It was a cross-sectional study of 300 patients with Vesiculobullous Disorders including all age groups attending a tertiary care centre over a span of 2 years. The diagnosis was made mainly by Clinical findings, Tznack smear and Histopathology. Result: In Vesiculobullous group of disorders, there were 137(45.67%) cases of infections, 111(37%) cases of immune-bullous disorders, 11(3.67%) cases of spongiotic disorders, 5(1.67%) cases of metabolic disorders, 3(1%) cases of genetic disorders, 16(5.33%) cases of bullous drug reaction, 15(5%) cases of inflammatory disorders, 1(0.33%) case of friction blister and of environmental disorder each. The highest incidence of Vesiculobullous disorders was found in age group 51-60 years (17.67%) followed by 21-30 years (16%).Incidence of Vesiculobullous disorders were more common in males (60.33%) and M: F ratio was 1.51:1. Conclusion: Correct diagnosis plays an important role in treatment and counselling about type, duration and prognosis of disease, maintaining remission and avoidance of aggravating or causative factors like drugs in cases of bullous drug reaction and stress in autoimmune Vesiculobullous group. Overcrowding, poor hygiene, low socioeconomic class, favourable environmental factors were mainly responsible for infections being most common in our study. [Gangawala V Natl J Integr Res Med, 2023; 14(3): 31-38, Published on Dated: 18/05/2023]