Assessment Of Carotid Sonographic Parameter Pulsatility Index Associated With Stroke Risk Among Hypertension With Diabetic Stroke Patients Compared To Hypertension With Diabetic Controls

Assessment Of Carotid Sonographic Parameter Pulsatility Index

Abstract

Background: Stroke is major public health problem leading to increased morbidity and mortality. Stroke is one of the leading causes of death and disability in India. Carotid sonographic hemodynamic parameter Pulsatality Index by using carotid Doppler Ultrasound is associated with the future risk of development of cerebrovascular stroke. Material And Methods: The present cross sectional study was conducted on 25 hypertension with diabetes stroke (Group A) and 30 hypertension with diabetes controls (Group B). CCA peak systolic velocity, end diastolic velocity and Pulsatility Index were assessed in each group by Doppler ultrasound machine. BMI and W/H was measured according to WHO protocol. Blood pressure was measured by sphygmomanometer. Biochemical analysis like Lipid profile and HbA1c were done by autoanalyser machine. Result: CCA PSV in Group A was found to be 65.50±21.58 and 69.75±15.51 in left and right side respectively & 70.51±16.70 and 68.64±13.73 in Group B. CCA EDV in Group A was found to be 13.56±2.78 and 11.53±4.65 in left and right side respectively & 20.32±4.54 and 18.17±4.39 in Group B . The data was highly significant (p<0.0001). CCA MV in Group A was found to be 39.53±11.72 and 40.64±9.25 in left and right side respectively & 45.41±9.39 and 43.40±7.70 in Group B (p=0.04 & p=0.23 left and right side respectively). CCA PI in Group A was found to be 1.28±0.15 and 1.44±0.22 in left and right side respectively & 1.05±0.23 and 1.14±0.16 in Group B . The data was highly significant (p<0.0001).Age in Group A and B was found to be 62.20±9.60 and 54.66±9.01 respectively (p<0.004). BMI in Group A and Group B was found to be 28.27±1.17 and 26.35±1.45 respectively (p<0.0001).W/H in Group A and Group B was 0.88±0.04 and 0.86±0.02 respectively (p=0.01). Systolic and diastolic blood pressure in both the groups was found to be 148.16±15.21 & 138.72±6.91 and 87.60±5.94 & 83.86±6.23 which was statistically significant with p=0.003 & p=0.02. The difference between mean of two groups for HbA1c, HDL , LDL , total cholesterol and triglyceride in both the groups were 8.6±0.82 &7.45±0.56, 39.04±5.85 & 49.97±8.34, 143.20±6.40 &113.26±17.09, 226.28±8.28 & 201.90±21.83 & 195.68±9.69, 201.03±55.82 respectively in which HbA1c, HDL, LDL, Total cholesterol were statistically very significant(p<0.0001) and triglyceride was not statistically significant. Conclusion: In conclusion, among hemodynamic parameters that are measured by carotid Doppler ultrasound, Pulsatility Index may play a role for predicting cerebrovascular stroke in hypertension with diabetic patients. In this sense, we concluded that Pulsatility Index examination should be carried out in hypertension with diabetic patients by carotid Doppler ultrasonography. These findings need to be confirmed by a prospective study. [Gadhvi H sain A Natl J Integr Res Med, 2020; 11(3):11-14]