Cord Blood Iron Status In Maternal Iron Deficiency Anaemia

Cord Blood Iron Status In Maternal Iron Deficiency Anaemia


  • Dr. Vandana Agrawal
  • Dr. Vaishali Jain
  • Dr. Priti Sahu


Iron deficiency anaemia, cord blood , haemoglobin , ferritin


Background: Iron deficiency (ID) and iron-deficiency anaemia (IDA) during pregnancy continue to be of
worldwide concern.The purpose of this study was to determine the effect of maternal iron status on neonatal iron
status and anthropometric characteristics.Methodology: A total of 86 pregnant women aged between 19 and 31
years delivering singleton live births at term gestation (37-41weeks) were included in the study. The pregnant women
were divided into three groups according to their pre-delivery haemoglobin (<11gm/dl) and serum ferritin
concentration (<12ng/dl) levels. Analysis of maternal and cord blood for estimation of haemoglobin level and serum
ferritin was performed. Weight, length and head circumference of neonates was also recorded. Results: Amongst the
pregnant women, 32.6% were anaemic and 17.4% were iron deficient. Neonatal haemoglobin and neonatal serum
ferritin was significantly different (p<0.001) across 3 groups suggesting that maternal anaemia affected the iron
status including iron stores of the newborn. Neonatal haemoglobin and neonatal serum ferritin had a significant
positive correlation with maternal iron status. However no significant correlation was found between maternal iron
status and neonatal anthropometric parameters except in case of neonatal birth weight which had a significant
positive correlation with maternal haemoglobin levels. Conclusion: This study showed that maternal iron deficiency
anaemia has an adverse effect on iron status of their newborns. Thus effective strategies are urgently needed to
control maternal anaemia in the developing world. [Agrawal V NJIRM 2016; 7(3):21 - 24]


1. International Institute for Population Sciences and
ORC Marco 2000. National Family Health Survey
(NFHS-2), 1998–99. Mumbai, India: International
Institute for Population Sciences and ORC
2. Toteja GS, Singh P. Micronutrient profile of Indian
population.: Indian Council of Medical Research,
National Workshop on Micronutrients. Background
Documents. New Delhi, India: Indian Council of
Medical Research;2003
3. Allen LH. Pregnancy and iron deficiency:
unresolved issues. Nutr Rev. 1997; 55(4):91-101.
4. Scholl TO. Iron status during pregnancy: setting the
stage for mother and infant. Am J Clin
5. Lozoff B, Wolf AW, Jimenez E. Iron deficiency
anaemia and infant development : Effects of
extended oral iron therapy. J Pediatr.1996;
6. Sakande J et al.Maternal and neonatal iron status
in ivory coast. sante’ 2004 14(1):17-20
7. Emery D, Barry D. Comparison of Maori and non-
Maori maternal and fetal iron parameters. New
Zealand medical journal, 2004, 117(1195):909–13.
8. Erdem A, Erdem M, Arslam M, Yazici G, Eskandari
R. The effect of maternal anemia and iron
deficiency on fetal erythropoiesis. J Matern Fetal
Neonatal Med, 2002; 11 (5): 329– 32.
9. Kumar A, Rai AK, Basu S, Dash D, Singh JS. Cord
Blood and breast milk iron status in maternal
Anemia. Pediatrics. 2008; 121 (3): 673-77.
10. Paiva ADA, Rondó PHC, Pagliusi RA, Latorre RDO.
Relationship between the iron status of pregnant
women and their newborns. Rev. Saúde. Pública.
2007; 41(3): 1-7.
11. Siddique H, Ayyub M, Nadeem M .Correlation of
iron status between Pregnant women and their
corresponding newborns.Journal of Rawalpindi
Medical College ;2013;17(1):84-87.
12. Wu G , Bazer FW, Gudd TA, Meininger CJ, Spencer
TE. Maternal Nutrition and fetal development .J
Nutr: 2004;134(9):2169-2172.
13. Shukla MK et al .A longitudinal study on anaemia
of pregnancy in a rural population of Uttar
Pradesh. Indian Journal of Medical
14. Singla PN, Tyagi M, Kumar A,Dash D,Shankar R
.Fetal growth in maternal anaemia.J
15. Jaime-Perez JC, Herrara-Garga JL, Gomez-
Almaguer. Suboptimal fetal iron acquisition under
a maternal environment. Arch. Med. Res. 2005; 36
(5): 598– 602.
16. El-Farrash RA, Ismail EA, Nada AS.Cord blood iron
profile and breast milk micronutrients in maternal
iron deficiency anemia. Pediatr. Blood. Cancer.
2012; 58 (2): 233-38.
17. Scholl TO, Hediger ML, Fischer RL, Shearer JW.
Anemia vs iron deficiency: increased risk of
preterm delivery in a prospective study. Am. J.
Clin. Nutr. 1992; 55: 985–88.




How to Cite

Agrawal, D. V., Jain, D. V., & Sahu, D. P. (2018). Cord Blood Iron Status In Maternal Iron Deficiency Anaemia: Cord Blood Iron Status In Maternal Iron Deficiency Anaemia. National Journal of Integrated Research in Medicine, 7(3), 21–24. Retrieved from



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