Antibiotic Susceptibility Pattern Among CSOM Patients Attending AIMSR
Antibiotic Susceptibility Pattern Among CSOM Patients Attending AIMSR
DOI:
https://doi.org/10.70284/njirm.v7i1.1058Keywords:
CSOM, Antimicrobial sensitivityAbstract
Background and Aim: CSOM causing deafness is seen in more than one third of the population in developing countries and is responsible for more than two thirds of deafness in children thereby causing intellectual and educational problems which have a profound impact on the society. Knowledge of the pathogens responsible for CSOM and their antibiotic sensitivity can assist in the selection of the appropriate treatment regimen in these cases. Objective: To identify the bacteria causing CSOM in our hospital area and to determine their antibiotic sensitivity. Methodology: Prospective study of 20 samples from clinically suspected cases of CSOM was performed over a period of two months. Samples were subjected to culture and the isolates were identified by standard biochemical tests. Antibiotic sensitivity testing was performed by modified Kirby-bauer disc diffusion technique as per CLSI guidelines. Results: The predominant organism isolated was Staphylococcus aureus. No other organism was isolated in our study. The antimicrobial sensitivity of the isolates in our study showed 100% sensitivity to ciprofloxacin,ofloxacin and netilmycin followed by 75% sensitivity to cefotaxime and ceftriaxone. Conclusion: The bacterial pathogens causing CSOM are unique to each geographical area. There is a high carriage of Staphylococcus aureus strains in the external auditory canal and upper respiratory tract prevalent in our hospital area. Quinolones and third generation cephalosporins are the most effective drugs for CSOM in our hospital area and can be considered for empiric therapy of these cases. [Gandham P NJIRM 2016; 7(1):108-111]
References
2. Sateesh Kumar M, Saileela K, Rajendra Bhanudas S ,Trinain Kumar C . Study of aerobic bacterial isolates and their antibiotic susceptibility pattern in chronic suppurative otitis media. Indian Journal of Otology 2012;18(3):136-139.
3. Yorgancilar E, Yildirim M ,Guru R ,Bakir S ,Tekin R , Gocmez C,Meric F.Complications of chronic suppurative otitis media : a review. Eur Arch Otorhinolaryngol 2013;270(1): 69-76.
4. Madana J , Yolmo D ,Kalajarasi R , Gopalakrishnan S, Sujatha S. Microbiological profile with antibiotic sensitivity pattern of cholesteatomatous chronicsuppurative otitis media among children. Int J Pediatr Otorhinolaryngol 2011;75:1104-8.
5. Divya vaishnavi G.Aerobic bacteriology of chronic suppurative otitis media- A Hospital Based Cross sectional study. IJSR2015;4(6):607-609.
6. Harvinder K ,Sonia S .Bacterial and Fungal Study of 100 cases of chronic suppurative otitis media.JCDR 2011;5(6):1224-1227.
7. Okesola AO, Fasina OA. Trends in the Resistance Pattern of Bacterial Pathogens of Otitis Media in Ibadan , Nigeria. AFR.J.CLIN.EXPER.MICROBIOL 2012;13(1):46-50.
8. Asifa N , Kadri SM. Aerobic bacteriology of chronic suppurative otitis media: a hospital based study. Int J Res Med Sci 2014;2(40;1521-1525.
9. MacFaddin J. 3rd ed. Philadelphia: Lippincott Williams and Wilkins; 1976. Biochemical Tests for Identification of Medical Bacteria.
10. Performance Standards for Antimicrobial Susceptibility Testing. Vol.1 No.1, M2 A9, Vol. 1. Pennysylvania, USA: Clinical and Antimicrobial Susceptibility testing Vol. 1 No. 1, M2 A9. Vol. 1
11. Laboratory Standard Institute; 2007. Clinical and Laboratory Standard Institute .
12. Fathima G, Shoaib M, Mohammad Zeeshan R , Syed B. Antimicrobial susceptibility pattern of Bacterial and Fungal Isolates from patients with chronic suppurative otitis media in perspective of emerging resistance . Pak J Otolaryngol 2013;39:49-53.
13. Paradise JL, Rochette HE, Colborn DK, Bernard BS, Smith OG, Kurs–Lasky M . Otitis media in 2253 Pittsburg area infants: Prevalence and risk factors
during the first two years of life. Pediatr 1997; 99; 318–333.
14. Swaroprani NB, Kardesai SG, Metgud SC. Aerobic Bacteriological study of chronic suppurative otitisd media with reference to MRSA and ESBL
15. SMU Medical Journal 2014;1(1): PP. 120 – 128
16. Couzos S, Lea T, Mullar R, Murray R, Culbong M. Effectiveness of ototopical antibiotics for CSOM in Aboriginal children, a community based multicentre double blind randomized controlled trial. Med J Aust. 2003;179(4):185–190.
17. Podoshin L, Fradis M, Ben David J. Ototoxity of ear drops in patients suffering from chronic otitis media. J Laryngol Otol. 1989;103:46–50
18. Deb T, Ray D. A Study of the Bacteriological Profile of Chronic Suppurative Otitis Media in Agartala. Indian Journal of otolaryngology and Head & Neck Surgery. 2011:1-4.
19. English MG,Northern JL, Fria T. Chronic otitis media as a cause of Sensori-neural hearing loss. Arch Otolaryngol1973; 98:18–22.
