Study of Effect of Ferrous Carboxymaltose on Postpartum Anemia

Abstract

Background: The incidence of post-partum anemia (PPA) is 14-24%. Treatment of PPA with injectable iron
replenishes the iron store. Ferric carboxy-maltose complex (FCM) is an intravenous iron agent designed to be
administered in large doses in a short period of time. This study aims to find the efficacy and safety of FCM in
treating postpartum anemia. Materials And Methods : The present study is a Prospective interventional hospital
based therapeutic trial conducted on postpartum anemic women of more than 18 years of age with HB <10gm.
Intravenous ferric carboxy-maltose (FCM) was given to the anemic women who has just delivered. Total 500
mg/10 ml in 250 ml of 0.9% normal saline was given over 15-20 min. Result : Mean hemoglobin level before
intravenous ferric carboxy maltose was 8.1+/-0.4gm% while it was 10.05+/-0.6 gm% after treatment. Hb level,
Serum ferritin, MCV and MCHC improved after 2 weeks of treatment. Conclusion : FCM was well tolerated and
effectively increased mean hemoglobin levels in postpartum women. The duration of hospital stay also shortened
and their were no serious side effects noted with the use of FCM.