Study of Hypothyroidism in Pregnancy and its Association to Development of Pre-Eclampsia

Abstract

AIMS: To study association of development of pre-eclampsia in hypothyroid cases. To study outcome and infertility
association in hypothyroid cases. SUBJECTS AND METHODS : It is an observational study of 87 antenatal
hypothyroid patients. Association of hypothyroidism to infertility noted. Patients were followed for the development
of pre-eclampsia and outcome. RESULTS : There is 13.79% development of pre-eclampsia in hypothyroid cases,
more so in patients with S.TSH level >8mIU/L. Hypothyroidism is also associated with infertility. CONCLUSION :
The Odd's Ratio for development of pre-eclampsia in hypothyroid cases with S.TSH level >8mIU/L is 1.94 showing
positive correlation between hypothyroidism and development of pre-eclampsia.