Intralesional Bleomycin in the treatment of Orbital Lymphangioma- Original Article

Abstract

A prospective study of 15 patients of orbital lymphangioma, diagnosed clinically and radiologically, is presented.
Age of patient varied from 2 to 45 years. Treatment of patients was combination of intralesional injection Bleomycin
in all patients with surgical excision in some where cyst was anteriorly situated. Dose of drug was 0.5 mg /Kg body
weight, not exceeding 10 units at a time. A 24 g needle was passed into the orbital cyst and fluid was aspirated.
Keeping needle in same position, drug was injected into the cyst. Follow up after 6 months,4 patients had total
regression clinically and on B scan .Seven patients had partial regression and injection was repeated. In 2 patients
as mass was anteriorly situated, surgical excision with injection of dye in posterior lesions. In 2 patients there were
residual asymptomatic cysts in posterior part and so patients were kept under observation. No significant side
effects were observed.