Stiff Leg Syndrome : A Case Report

Abstract

Stiff person syndrome (SPS) is a rare disorder characterized by progressive fluctuating muscular rigidity and
spasms. Glutamic acid decarboxylase (GAD) antibody is primarily involved in the pathogenesis of SPS. Stiff leg
syndrome (SLS) is a newly emerging entity considered as focal form of SPS in which symptoms are confined to
distal limb usually the leg although sometimes this progresses to involve the axial musculature as well. Here we
report a case of stiff leg syndrome confirmed by electromyography with high serum level of GAD antibodies.