Misoprostol in the Management of Missed Abortion

Abstract

Objectives:The aim of study is to evaluate the safety, efficacy and reliability of regimen of vaginal misoprost as a
medical method of termination in 1st& 2nd trimester missed abortion.
Method :
It is a prospective study carried out in90 women of missed abortion confirmed by transvaginal ultrasound. After
fitness and consent, Misoprostol tablet 200 μgm was inserted vaginally every 4 hours of maximum 5 doses. Time
for latent period and induction abortion interval was noted and all patients monitored carefully. Surgical evacuation
was performed when complete exclusion was not documented on ultrasound after 24 hours of treatment.
Result :
Complete medical evacuation occurs in 54 women ( 60% )
Mean induction abortion interval was 13.37 hours
Conclusion :
Misoprost is a safe reasonably effective medical method in inducing complete evacuation in missed abortion.