A Rare Case of Anaplastic Astrocytoma of Corpus Callosum with Intraventricular Extension

Abstract

Introduction:- Though gliomas are the most frequent primary neoplasm in brain, only 3.8% infiltrate white matter
structures like corpus callosum. Corpus callosum involvement based on preoperative imaging is an unfavorable
prognostic factor for survival among the subgroup of young, good-performance-status patients with high-grade
astrocytoma.
Methodology:- 28 year lady was brought with history of left sided weakness and headache since 1 month and
history of convulsion 1 day back. Mri brain with contrast showed ill defined, cystic lesion arising from body of corpus
callosum of size 70*62*54 mm. Patient was operated for right frontal craniotomy and excision of corpus callosal
lesion with intraventricular extension and histopathology was anaplastic astrocytoma (who grade 3). Post
operatively patient headache and improved power.
Conclusion:- Gliomas of corpus callosum have aggressive behaviour, surgical complications and recurrence. If
treated properly these patients can have better postoperative outcome and prolonged survival.