Global Journal of Medicine & Public Health https://nicpd.ac.in/ojs-/index.php/gjmedph <p>The GJMEDPH is a peer-reviewed, open access journal, with an international editorial board. It is an initiative of the Regional Institute of Health and Family Welfare, Directorate of Health Services, Kashmir, India. The Institute was established under the India Population Project VII (IPP) with assistance from the World Bank and is meant to serve as an apex institution for the continuing education of in-service health professionals and staff from non-profit, non-governmental organisations involved in health activities.</p> en-US kadrism@gmail.com (Editor in Chief SM Kadri) kadrism@gmail.com (Editor in Chief SM Kadri) Sun, 13 Apr 2025 14:47:42 +0000 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 The association between mHealth wearables and hypertension selfmanagement in African-born immigrants from medically underserved areas in the United States: a causal-comparative study https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4125 <p><strong>Background </strong></p> <p>Hypertension remains a major global health concern, increasing the risk of heart disease and stroke. It affects over</p> <p>1.3 billion adults globally and nearly half the US adult population (47.3%), or 116 million individuals. African-born</p> <p>immigrants (40.2%) are disproportionately affected compared to 30% for other ethnic groups. A significant portion</p> <p>of Americans (67 million) have uncontrolled hypertension. Using mHealth interventions, especially</p> <p>wearable devices, has shown some potential in improving hypertension control and treatment compliance in ethnic</p> <p>minorities.</p> <p><strong>Methods </strong></p> <p>This causal-comparative study conducted in 2024 aimed to determine if there is an association between using</p> <p>mHealth wearable devices and improving hypertension control in African-born immigrant groups. The inclusion and</p> <p>exclusion criteria consisted of having a hypertension diagnosis, being 45-75 years old, reading at a third-grade level,</p> <p>and living in a medically underserved primary care area (MUA). A t-test was used to compare the mean arterial</p> <p>pressure data in two groups.</p> <p><strong>Results </strong></p> <p>All 100 participants from nine MUAs were randomly divided into two equal groups. Group 1 used a smart watch (the</p> <p>mHealth group) to measure their blood pressure, whereas Group 2 (the usual care group) used an automated blood</p> <p>pressure monitor. The study yielded two statistically significant results, including 1) the mean arterial pressure at</p> <p>the end of six weeks was lower in the mHealth group than in the usual care group (<em>p </em>&lt; 0.001) with a -4 mmHg</p> <p>difference. The mHealth group participants achieved a better mean arterial pressure with a -3 mmHg reduction in</p> <p>mean arterial pressure (<em>p </em>= 0.005).</p> <p><strong>Conclusions </strong></p> <p>The study suggested that African-born immigrants can benefit from using mHealth wearable devices to improve</p> <p>hypertension management. It contributed to the understanding of factors associated with the higher prevalence of</p> <p>hypertension among African-born immigrants. It aligns with ongoing efforts to uncover novel approaches for</p> <p>assisting minority populations in low-resource settings to control hypertension using mHealth wearable devices.</p> Nelson Bryant Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4125 Sun, 13 Apr 2025 00:00:00 +0000 Prevalence of Anemia and Its Association with Dietary Restrictions Among Pregnant Women in Eastern Gujarat's Tribal Communities https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4126 <p><strong>Context </strong></p> <p>Anaemia is a very common health problem seen in developing countries. It leads to poor outcomes in pregnancy</p> <p>and complicates the life of the newborn in certain cases. In multiple surveys conducted over the years it is noted</p> <p>that the diet plays an important role in development of Anaemia, varying in the micronutrient intake, geographical</p> <p>location and season.</p> <p><strong>Objectives </strong></p> <ol> <li>To assess the prevalence of Anaemia tribal women</li> <li>To assess the association of food restriction with Anaemia.</li> </ol> <p><strong>Method </strong></p> <p>A descriptive cross-sectional study was conducted in a tribal district of Eastern Gujarat. This study was conducted</p> <p>at Anganwadi centre.The sampling type was purposive sampling, all those women who were pregnant and were in</p> <p>15–49-year-old age groups, who were willing to take part in the study were included.Their hemoglobin levels were</p> <p>evaluated for anaemia and they were evaluated for food related deficiencies through a self-administered</p> <p>questionnaire. 80 women were included in the study and descriptive analyses was conducted to calculate</p> <p>frequencies with percentages and proportions of categorical variables in the total study sample. Chi-square tests</p> <p>were used to assess association of various food restrictions and anemia</p> <p><strong>Results </strong></p> <p>The mean hemoglobin of the study was 9.6+1.9 g/dl, prevalence of anemia was 76.25 %, out of which 85% of the</p> <p>population had mild anemia. A significant association was noted between food restriction/avoidance and Anaemia</p> <p>with a p value of 0.019.</p> <p><strong>Conclusion </strong></p> <p>Food restriction during pregnancy is associated with Anaemia in Pregnancy.</p> <p>&nbsp;</p> Niyati Harshadkumar Zaveri, Mohabatsinh Baria, Jitendra S. Parmar, Manjula J. Babariya , Aman Damor, Sanjay Kumar, .Rahul Tahilramani Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4126 Sun, 13 Apr 2025 00:00:00 +0000 Mannose binding lectin as a marker for coronary artery disease in hypertension https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4127 <p><strong>Background </strong></p> <p>According to The Framingham Heart Study and the Epidemiology of Cardiovascular Diseases hypertension is an</p> <p>independent risk factor for cardiovascular disease (1). Inflammation plays a major role in atherosclerosis. Markers</p> <p>of innate immunity have been shown to predict the development of coronary artery disease. MBL (Mannose binding</p> <p>lectin) being a component of innate immunity can be used as a marker of cardiovascular risk in hypertension.</p> <p><strong>Aim &amp; Objectives: </strong></p> <p>The study was conducted to evaluate the risk of coronary artery disease in recently diagnosed hypertensive patients</p> <p>by estimating serum mannose binding lectin levels</p> <p><strong>Materials &amp; Methods: </strong></p> <p>This cross sectional case control study was conducted among 180 subjects who were divided into three groups as</p> <p>follows</p> <p>Group A : 60 recently diagnosed hypertensive patients ( &lt; 6 months duration )</p> <p>Group B : 60 hypertensive patients who had myocardial infarction recently (&lt; 7 days)</p> <p>Group C : 60 age &amp; sex matched healthy controls</p> <p>Serum levels of MBL was evaluated in the three groups using ELISA technique. Collected data were analysed</p> <p>statistically.</p> <p><strong>Results &amp; Conclusion: </strong></p> <p>The serum MBL levels were significantly elevated in hypertensive patients (mean = 823.45 ng/mL; Range – 772 to</p> <p>875 ng/mL) and in hypertensive with myocardial infarction (mean = 1163.39 ng/mL; Range – 945 to 1381 ng/mL) as</p> <p>compared with control population (mean = 607.15 ng/mL; Range – 513 to 701 ng/mL) with p value of 0.001. From</p> <p>the ROC curve, it has been determined that MBL has sensitivity of 93% &amp; specificity of 96%) with a positive</p> <p>predictive value of 96% &amp; negative predictive value of 84.65%.</p> <p>Our findings suggested the determination of MBL status may serve as a potential marker for early identification of</p> <p>patients at risk of cardiovascular complications, pending further validation studies.</p> <p>&nbsp;</p> M Dilagamari, V.Amuthavalli Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4127 Sun, 13 Apr 2025 00:00:00 +0000 Determinants of communication dynamics on doctor-patient interactions: a descriptive cross-sectional investigation https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4128 <p><strong>Introduction: </strong>Communication dynamics in doctor-patient relationships are vital for improving patient outcomes,</p> <p>with effective communication fostering clear understanding, information gathering, and compassionate</p> <p>relationships. Studies highlight that physician communication skills lead to earlier problem detection, better</p> <p>outcomes, higher satisfaction, and improved adherence to treatment plans. While factors like patient</p> <p>demographics, doctor characteristics, and environmental influences affect doctor-patient communication,</p> <p>research is limited, especially in the context of rising violence against doctors and legal challenges.</p> <p><strong>Objectives: </strong>Our study aimed to evaluate patients’ perceptions and identify the determinants associated with</p> <p>negative perceptions of communication dynamics in doctor-patient interactions.</p> <p><strong>Methods: </strong>The community-based cross-sectional study included 230 participants (?18 years) selected via simple</p> <p>random sampling and was conducted in Angadipuram panchayat, North Kerala, India. A pre-tested validated</p> <p>questionnaire collected socio-demographic data, DPC effectiveness, and influencing factors. Data were analyzed</p> <p>using SPSS 26, with chi-square tests for bivariate analysis (<em>p </em>? 0.05).</p> <p><strong>Results: </strong>Our study found that 61.3% (n=141) of participants reported positive doctor-patient interactions, with</p> <p>75.3% (n=55) aged 31-45 years reporting good communication and 86.9% (n=106) of females expressing higher</p> <p>satisfaction levels (p=0.001). Attentive listening and involvement in decision-making (p=0.001) positively influenced</p> <p>DPC, while factors like religious/cultural influences (p=0.001), high fees (p=0.0001), and rude staff behaviour</p> <p>(p=0.0001) were linked to poorer communication experiences.</p> <p><strong>Conclusion: </strong>Our study emphasized that doctor-patient communication was shaped by various demographic and</p> <p>contextual factors. While many participants reported positive interactions, challenges such as religious/cultural</p> <p>influences, high fees, and staff rudeness pose significant barriers, emphasizing the need for patient-centered</p> <p>communication strategies to improve healthcare quality and satisfaction</p> Narayanan Namboothiri G, Ajith V, Herma Fathima, Hiba Saleem K T, Hibah Moideen Hakim, Hina C, Hisham Aboobacker Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4128 Sun, 13 Apr 2025 00:00:00 +0000 Prevalence and risk factors of type 2 diabetes mellitus in a rural and an urban Nigerian community: Are the demographics changing? https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4129 <p><strong>Background </strong></p> <p>The prevalence of Diabetes Mellitus (DM) is increasing at an alarming rate globally and in sub-Saharan Africa,</p> <p>Nigeria inclusive. Previous community-based studies in Nigeria, including studies in Abia State have demonstrated</p> <p>a high prevalence of DM, with no significant difference between the rural and urban areas in the previous study</p> <p>done in Abia State.</p> <p><strong>Objective </strong></p> <p>To evaluate the prevalence and risk factors of DM in urban and rural communities of Abia State, South-Eastern</p> <p>Nigeria.</p> <p><strong>Method </strong></p> <p>A cross-sectional comparative study of 2800 adults, comprising equal numbers of rural and urban residents of Abia</p> <p>State was conducted. Data was obtained using interviewer administered semi-structured questionnaires (Appendix</p> <p>1). Blood pressure, anthropometric indices and fasting blood glucose were obtained for each of the participants.</p> <p>Data analysis was done using SPSS version 20.</p> <p><strong>Results </strong></p> <p>The mean age of the respondents was 48.54 ± 13.24 years, with the rural residents being significantly older than the</p> <p>urban, (54.23 ± 14.26 and 42.85 ± 13.24 years, respectively p&lt;0:001). Male to female ratio was 1:2.5, (p&lt;0.001).</p> <p>Diabetes mellitus was observed in 8% of the respondents (urban = 8.9% and rural = 7.2%, p=0.110). Independent</p> <p>predictors of DM in this study included age, family history of DM, daily intake of fruits in processed forms and</p> <p>hypertension in the urban area, while in the rural area are age and family history of DM.</p> <p><strong>Conclusion </strong></p> <p>The prevalence of DM is rising in Abia State, with no significant urban-rural difference as observed in previous</p> <p>studies in the state.</p> Ubani BC, Nkpozi MO, Ekrikpo UE, Ekuma I, Young EE, Unachukwu CN Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4129 Sun, 13 Apr 2025 00:00:00 +0000 Health seeking behavior among interstate migrant workers in a northern district of Kerala https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4130 <p><strong>Background </strong></p> <p>Throughout history, people have migrated for better opportunities, impacting political and economic landscapes.</p> <p>Recently, there’s been more focus on internal migration challenges, especially in India, where states like Kerala</p> <p>attract many interstates migrant workers. Despite their economic contributions, migrant workers face significant</p> <p>health challenges and limited access to healthcare. This study aims to evaluate the health-seeking behaviour of</p> <p>interstate migrant workers in a northern district of Kerala and identify influencing factors.</p> <p><strong>Methods </strong></p> <p>In this cross-sectional study, 400 interstate migrant workers who lived in selected municipalities in the Malappuram</p> <p>district of Kerala were surveyed using a semi-structured interview schedule in the participants native languages with</p> <p>the assistance of an interpreter, with an emphasis on health-seeking behavior, and sociodemographic information.</p> <p>Data analysis utilized descriptive statistics and chi-square tests via SPSS software.</p> <p><strong>Results </strong></p> <p>The mean age of participants was 31.3 ±7.7 years. Most preferred was private healthcare (39.8%) and 32% utilized</p> <p>government facilities. 54% are willing to visit a doctor or healthcare facility when ill, 35% use home treatments,46%</p> <p>practice self-medication when sick. Socio-demographic factors such as age and income significantly influenced</p> <p>health-seeking behaviors, with a preference for modern medicine (88.3%).</p> <p><strong>Conclusions </strong></p> <p>The study on interstate migrant workers in Malappuram district, Kerala, reveals crucial insights into their health</p> <p>seeking behaviors and socio-economic conditions. The study identifies high incidences of inadequate healthcare</p> <p>access and frequent reliance on self-medication and home remedies. The study highlights the impact of</p> <p>sociodemographic determinants on health behaviors and access to care.</p> <p>&nbsp;</p> Ajith V, Mubarack Sani T. P, Nandini G, Jamaludheen C, Nidhun P Krishnan, Ashwin Raj K K, Krishnaraj Rajeev, Sneha Rajan Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4130 Sun, 13 Apr 2025 00:00:00 +0000 A Cost Analysis of Rheumatic Fever Management in Jamaica, 2012 to 2018 https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4131 <p><strong>Background </strong></p> <p>Introduction: Jamaica’s burden of Acute Rheumatic Fever (ARF) and sequelae like Rheumatic Heart Disease (RHD)</p> <p>have declined significantly since introduction of the WHO prevention programme in 1984 and has resulted in</p> <p>reduced expenditure in prevention and control. This research aims to determine direct costs of Rheumatic Fever</p> <p>(RF) events, compare them to expenditures recorded in the literature, and assess recommendations for investment</p> <p>and prioritization.</p> <p><strong>Methods </strong></p> <p>A national cross-sectional survey was conducted to estimate inpatient, outpatient and prevention costs for each of</p> <p>four RF groups (ARF, RHD with and without heart Failure, and Carditis). Medical records were accessed for all</p> <p>patients recorded in the Hospital Active Surveillance Registries (2012 to 2018) from five major regional and</p> <p>specialist hospitals. Relevant data were abstracted using an internally developed, pretested tool. Categorical costs</p> <p>were calculated using the average number of units used per sub-category (e.g. registration, room and board,</p> <p>consumables, tests, medications) and multiplied by National Health Service fees.</p> <p><strong>Conclusion </strong></p> <p>From 156 reports of ARF/RHD, 74 patients were identified as suspected or confirmed, of which 44 had demographic</p> <p>information: 58.1% were male, and onset of ARF and RHD respectively were at 11.5 (SD 6.9) and 20.8 (SD 12.3)</p> <p>years. The direct country cost of care was US$78,249.88 annually, averaged across all RF/RHD clients. The single</p> <p>most costly component was inpatient admission, of which RHD, then ARF/Recurrent RF were costliest at US$695.30</p> <p>and US$605.28 respectively. Secondary prophylaxis costs US$56.42/patient/year (US$36,189.16 nationally/year)</p> <p>in optimal circumstances, and US$49.12 at the actual 67% compliance rate. At US$4.78/case, the annual cost of</p> <p>pharyngitis management for at-risk 0-15 years olds was US$159,377.11.</p> <p><strong>Interpretation </strong></p> <p>Previous local data suggests that the total cost of care of RF conditions has fallen significantly since prevention</p> <p>programme initiation. Adjusted for government subsidy, Jamaica’s direct ARF inpatient costs (US$2,421.12) are</p> <p>comparable to the WHO-CHOICE inpatient estimate (US$2,225.57). These further approximate if local meal costs</p> <p>are excluded as CHOICE estimates do. We believe the changing epidemiology of RF warrants prioritization for pre</p> <p>and peri-natal RHD care, compliance boosting activities for prophylaxis, and clinical decision rules with rapid</p> <p>antigen detection tests for targeted point of care diagnosis, all in keeping with global recommendations.</p> Yohance Rodriguez, Camille-Ann Thoms Rodriguez Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4131 Sun, 13 Apr 2025 00:00:00 +0000 Lemierre’s syndrome: A case report of an infant with Acute Suppurative Otitis Media and Poly-microbial infection with Leuconostic Citreum and Acinatobacter Baumannii https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4132 <p>Lemierre’s syndrome is quite a rare condition characterized by septic thrombophlebitis of the internal jugular vein</p> <p>as a complication of head and neck infection, and septic embolization to other organs. The most common</p> <p>etiological agent is Fusobacterium necrophorum. It is very rarely reported in infants or secondary to Acute</p> <p>Suppurative Otitis Media (ASOM) or secondary to bacteria other than Fusobactrium Necrophorum. Here, we report</p> <p>rare findings of a rare disease, in the case of a 6month old female child who developed Lemierre’s syndrome as a</p> <p>complication of ASOM and her blood culture grew Acinatobacter baumannii and Leuconostic citreum. By the time</p> <p>of this study, very few cases of invasive infection in humans due to Leuconostic citreum have been reported.</p> <p>&nbsp;</p> Deepty Nauriyal, Sukhjinder Singh, Rishabh Dubey Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4132 Sun, 13 Apr 2025 00:00:00 +0000 Level of knowledge, attitude, and practice regarding emergency contraception pills among female undergraduate students at KCMUCo in the Moshi Municipality, Kilimanjaro, Tanzania https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4133 <p><strong>Background </strong></p> <p>Globally, unplanned pregnancies and unsafe abortions are prevalent among young and unmarried women aged 18</p> <p>years and above. Existing evidence shows widespread use of emergency contraception pills (ECP) may significantly</p> <p>reduce induced abortion-related morbidity and mortality. This study aimed to determine the level of knowledge,</p> <p>attitudes, and practice regarding ECP among female undergraduate students aged 15 years and above at a Medical</p> <p>University in Moshi Municipality in the Kilimanjaro region, Tanzania.</p> <p><strong>Methods </strong></p> <p>Using a descriptive cross-sectional study design with multistage random sampling, semi-structured questionnaire</p> <p>data were collected among 314 female students at Kilimanjaro Christian Medical University College (KCMUCo) from</p> <p>July 2024 to August 2024.</p> <p><strong>Results </strong></p> <p>Three hundred and fourteen (314) participants were enrolled (response rate 100%). The median age was 22 years</p> <p>(Interquartile range (IQR)= 2 years), the majority, 302 (96.2%) were in the age group of 15-25 years old, 309, (98.4%),</p> <p>were unmarried, 218, (69.4%)were Christians,169(53.8%) were enrolled in the Doctor of Medicine program, 44%</p> <p>(n=138/314), had had a sexual experience, and 60% (83/138) had their sexual debut between 14-19 years old. The</p> <p>majority, 87.9% (276/314), had heard about ECP, and 72% (198/276) mentioned the internet as the main source of</p> <p>information on ECP. More than half of participants, 58.8 %(n=168/287), had a high level of knowledge of ECP. More</p> <p>than half of participants, 54.4% (n=156/287), had positive attitudes towards ECP. 62%(85/138), had used ECP in the</p> <p>past, and predictors associated with ECP practices at multivariate analysis include social acceptability for female</p> <p>students to use ECP (Adjusted odds ratio (AOR) = 2.10 [95 % Confidence interval (CI) 1.00-4.31; P= 0.05], intention</p> <p>to use ECP in the future (AOR=3.01[2.30-8.64]; P=0.000), adequate knowledge of ECP (AOR=6.70[2.80-16.0];</p> <p>P=0.000), fear of side effects as a barrier to ECP use (AOR=0.23[0.11-0.48]; P= 0.05), and the belief that ECP can</p> <p>prevent STD (AOR = 0.32[0.12-0.85]; P=0.02).</p> <p><strong>Conclusion </strong></p> <p>Female graduate students had a high level of knowledge, and a positive attitude towards ECP, with the internet as</p> <p>the main source of information. Adequate level of knowledge, social acceptability of female students to use ECP,</p> <p>and intention to use ECP in the future are positively associated with ECP practices. Participants who reported fear</p> <p>of side effects of ECP, and the belief that ECP can prevent STDs, are less likely to use ECP. Despite a high level of</p> <p>knowledge and positive attitude towards ECP, reinforcing the respondent’s knowledge of specific details of ECP</p> <p>such as mechanism, efficacy, and typology may be beneficial for improving ECP practices among female</p> <p>undergraduate students at KCMUCo in Moshi Municipality.</p> <p>&nbsp;</p> Angel A Ng’unda, Mariana J Mung’au, Gloria E Foya, Jamida J Mateni, Bernard Njau Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4133 Sun, 13 Apr 2025 00:00:00 +0000 Addressing Underutilization of Antenatal Care in Sagar City: A Call to Action https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4134 <p>A cross-sectional survey was conducted among 400 postnatal mothers who accessed maternal and child health</p> <p>(MCH) services across different healthcare institutions, including district hospitals, medical colleges, primary health</p> <p>centers, and Anganwadi centers. Data collection took place from March 2020 to October 2021 using a pre-tested</p> <p>semi-structured questionnaire. Mothers from institutions were selected through convenient sampling, while simple</p> <p>random sampling was used for Anganwadi centers. Informed consent was obtained from all participants.Findings</p> <p>revealed high early registration rates but significant underutilization of ANC services. Although services were</p> <p>generally well-received, many women did not complete the recommended ANC visits, and iron-folic acid (IFA)</p> <p>supplementation adherence was inadequate. Key barriers included lack of awareness, affordability issues, and</p> <p>limited accessibility.</p> <p>To enhance ANC utilization, targeted interventions should focus on increasing awareness, improving affordability</p> <p>through financial incentives, strengthening service accessibility, and ensuring high-quality ANC delivery. Aligning</p> <p>these efforts with the Sustainable Development Goals (SDGs) related to maternal health can help bridge existing</p> <p>gaps and improve maternal health outcomes in Sagar.</p> <p>&nbsp;</p> Shefali Jain Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4134 Sun, 13 Apr 2025 00:00:00 +0000 Knowledge of Sexually Transmitted Infections with Focus on HIV/AIDS and Hepatitis B among Secondary School Adolescents in Ekiti State, Nigeria https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4135 <p>Sexually transmitted infections (STI) are a serious public health issue among adolescents because they often have</p> <p>limited knowledge and insufficient access to health services. Good knowledge of STIs, hepatitis B (HB) and the risk</p> <p>of developing diseases is essential to engage in preventive actions. The aim of this study is to assess the knowledge</p> <p>of STIs, including HIV/AIDS and HB among adolescents attending secondary school education in Ekiti State.</p> <p><strong>Methods </strong></p> <p>A cross-sectional study design was used in selecting 669 participants among secondary school adolescents from</p> <p>Ekiti State, Nigeria, through a multistage sampling technique. Data was collected using semi-structured, pre</p> <p>tested, self-administered questionnaires. SPSS version 26 was used for data analysis. The descriptive statistics</p> <p>involved percentages, sample mean, and frequency tables. Inferential statistics such as Chi-square were used to</p> <p>test for associations between categorical variables. P-values &lt; 0.05 were considered significant.</p> <p><strong>Results </strong></p> <p>The study included a total of 357 females (53.4%) and 312 males (46.6%), with 256 (38.3%) of participants below 14</p> <p>years old, and 407 (61,7%) older than 14 years old.611 (91.3%) subjects had awareness of HIV/AIDS, and 233 (34.8%)</p> <p>of participants were aware of the Hb virus. 330 (49.3%) of students had good knowledge of STIs, and the remaining</p> <p>339 (50.7%) of subjects were poorly informed on this topic. Being a male and age 14 years and above were</p> <p>significantly associated with good knowledge of STIs.</p> <p><strong>Conclusions </strong></p> <p>Awareness of HB infection is very low among adolescents from Ekiti state, Nigeria, and their knowledge of STDs is</p> <p>poor as well. Being a male and older adolescents are factors associated with having more knowledge of STIs. It is</p> <p>recommended that comprehensive education concerning STIs and sexually transmitted diseases and associated</p> <p>diseases should be started much earlier in life and especially for female adolescents.</p> <p>&nbsp;</p> Oluremi Olayinka Solomon, Olusoji Abidemi Solomon,, Eyitope Oluseyi Amu, Victor Mayowa Adeleye, Paul Oladapo Ajayi, Mojoyinoluwa Oyindamola Adeoson Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4135 Sun, 13 Apr 2025 00:00:00 +0000 Utilizing the association between Hepatitis B viral load and Hepatic failure biomarkers for guided antiviral therapy https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4136 <p><strong>Background </strong></p> <p>Hepatitis B virus infection is a global public health problem. Individuals with chronic Hepatitis B are at an</p> <p>increased risk of developing liver cirrhosis, hepatic failure and hepato cellular carcinoma. This study was</p> <p>undertaken in a tertiary care hospital with the aim to measure the Hepatitis B viral DNA and its association</p> <p>with hepatic biochemical markersso as to guide for better clinical management during therapy.</p> <p><strong>Methods and Material: </strong></p> <p>Blood samples from 94 Hepatitis B seropositive patients were collected and tested for HBV viral load by real</p> <p>time PCR.Patients were divided in two categories A &amp; B (A= &lt; 20000 IU/ml and B &gt;20000 IU/ml) as based on</p> <p>the quantification of viral DNA. Biochemical tests were performed for assessing Serum ALT, AST, Platelet</p> <p>count, hemoglobin, Albumin, Bilirubin and Prothrombin time.</p> <p><strong>Results: </strong></p> <p>Total patients in category A (&lt; = 20000 IU/ml) viral load were 51 (54%) Total patients in category B (&gt;20000</p> <p>IU/ml) were 43.Category B patients with &gt;20000 IU/ml of HBV viral load had elevated levels of SGOT (AST)</p> <p>with statistical significance at P value 0.038. Moreover, Serum albumin and Platelet count were significantly</p> <p>noted on lower side in category B patients at P values 0.03 and 0.02 respectively.</p> <p><strong>Conclusion: </strong></p> <p>Viral load of Hepatitis B varies over time, depending on the phase of theinfection. The findings of this study</p> <p>points at strong correlation between HBV viral load and biochemical markers for hepatic failure.Thus timely</p> <p>and regular viral load monitoring along with hepatic biomarkers is crucial for the treatment of Hepatitis B.</p> <p>&nbsp;</p> JitendraKumar S Parmar, Niyati H Zaveri, Shivaji D Patil, Manjula J Babariya, Varsha dhuliya, Bhavi Patel Copyright (c) 2025 https://creativecommons.org/licenses/by-nc-nd/4.0/ https://nicpd.ac.in/ojs-/index.php/gjmedph/article/view/4136 Sun, 13 Apr 2025 00:00:00 +0000