Pinna with synchronous chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) - A rare presentation of Amelanotic melanoma (Desmoplastic variant)
Pinna with synchronous chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL)
Keywords:
amelanotic melanoma (AM), desmoplastic variant, chronic lymphocytic leukemia(CLL), small lymphocytic lymphoma(SLL),lymph node, standardized incidence ratio (SIR)Abstract
Malignant melanoma is a neoplasm derived from cutaneous melanocytes, that frequently occurs in the elderly and, may metastasize loco-regionally or distally. B-cell chronic lymphocytic leukemia/small lymphocytic B-cell lymphoma (CLL/B-SLL) is a neoplasm of B-cell lymphocytes that also occurs frequently in the older population as an asymptomatic elevation of the white blood cell count (WBC) and has an overall good prognosis.
There is minimal data on simultaneous occurrence of CLL and melanoma. In this report, we describe the unusual case of a 74 years old man who was diagnosed as desmoplastic amelanotic melanoma, pinna in an unsuspected second clinical setting, with incidental synchronous detection of chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL) , highlighting the need for workup of such chance associations. Dense inflammatory granulation tissue in lesions of pinna need to be followed up, so as not to miss desmoplastic variant of amelanotic melanoma as in this case.
