Adult Onset Stills Disease: Rare But Not Uncommon

Adult Onset Stills Disease: Rare But Not Uncommon


  • Dr. Aakash Shah Resident Doctor, Department Of Medicine, Baroda Medical College. Gujarat


Adult Onset Stills Disease, Hyperferritinemia, Yamaguchi Criteria, Methotrexate, Pyrexia of unknown origin (PUO)


Adult Onset Stills Disease is a rare clinical entity without any known etiology which characteristically presents with fever, rash, arthritis, along with other systemic manifestations. We present the case of a 26 years old male presented with multiple joint pain, high grade fever and rash since 2months. The patient was extensively evaluated for pyrexia of unknown origin and treated with weeks of intravenous antibiotics without any benefit. Applying Yamaguchi’s criteria, he was diagnosed to have Adult Onset Stills disease. Patient responded very well to systemic steroids and fever and joint symptoms resolved completely. He required addition of methotrexate as steroid sparing agent as attempts of tapering prednisolone lead to recurrence of symptoms. AOSD remains a very rare but treatable cause of fever and joint pain and high index of suspicion is required for diagnosis. [Shah A Natl J Integr Res Med, 2020; 11(5):75-78]




How to Cite

Dr. Aakash Shah. (2020). Adult Onset Stills Disease: Rare But Not Uncommon: Adult Onset Stills Disease: Rare But Not Uncommon. National Journal of Integrated Research in Medicine, 11(5), 75–78. Retrieved from



Case Report