Study On Prevalence Of Hepatitis C Infection In Healthy And High Risk Groups
Study On Prevalence Of Hepatitis C
Keywords:
HCV-Hepatitis C Virus, hepatitis B, Thalesemia, Haemodialysis, ANC-Antenatal mothersAbstract
Background & objectives: Developing country like India shows high prevalence of hepatitis C on account of lack of universal precautions while treating patients. This kind of transmission is seen more in cases of Thalesemias on regular blood transfusion, with renal diseases on haemodialysis and co-infection with hepatitis B along with patients admitted in various wards for treatment. Study was conducted with the objective to find out prevalence of HCV infection in patients with hepatitis B, Thalesemias, patients undergoing haemodialysis, patients admitted in hospital for other diseases who are hepatitis B negative, Ante-natal cases and voluntary healthy blood donors. Methods: Blood was collected of 1040 persons from various groups with their consent. All the sera were tested for anti HCV antibody by ELISA and Signal HCV test. Results: Total twelve participants were found positive for HCV infection, majority were belonged to Thalesemic group and rest of the participants belonged to voluntary healthy blood donor group, patients of hepatitis B and patients on haemodialysis. Interpretation & conclusion: those who are at risk of getting Hepatitis C should undergo for HCV testing on regular interval.
References
2. Beenu Thakral, Neelam Marwaha, Y.K. Chawla, Karan Saluja, Arpita Sharma, R.R. Sharma R.W. Minz & S.K. Agnihotri. Prevalence & significance of hepatitis C virus (HCV) sero-positivity in blood donors. Indian J Med Res 2006; 124: 431-438
3. Makroo RN, Raina V, Kaushik V. Prevalence of hepatitis C virus antibody in healthy blood donors. Indian J Med Res 1999; 110: 123-5.
4. Choudhury N, Ramesh V, Saraswat S, Naik S. Effectiveness of mandatory transmissible diseases screening in Indian blood donors. Indian J Med Res 1995; 101: 229-32.
5. Jain A, Rana SS, Chakravarty P, Gupta RK, Murthy NS, Nath MC, et al. The prevalence of hepatitis C virus antibodies among the voluntary blood donors of New Delhi, India. Eur J Epidemiol 2003; 18 : 695-7.
6. Arankalle VA, Chadha MS, Jha J, Amrapurkar DN, Banerjee K. Prevalence of anti HCV antibodies in Western India. Indian J Med Res 1995; 101: 91-3.
7. Deshpande A, Kumar A, Khodaiji S, Gupta AD. Prevalence of hepatitis C virus antibody in healthy blood donors. Indian J Hemat Blood Transf 1998; 16: 71-2.
8. DR Arora, R Sehgal, N Gupta, A Yadav, N Mishra, SB Siwach. Prevalence of parenterally transmitted hepatitis. Viruses in clinically
diagnosed cases of hepatitis. Indian Journal of Medical Microbiology, (2005) 23 (1):44-4
9. Esteban JI, Genesca J, Alter HJ. Hepatitis C: Molecular biology, pathogenesis, epidemiology, clinical features and prevention. In: Boyer JL, Ockner RK, editors. Progress in Liver Diseases. Vol.10, Philadelphia: W.B. Saunders; 1992: 253-82.
10. Sumarthy S, Valliammai T, Thyagarajan SP, Malathy S, Madanagopalan N, Sankaranarayanan V, et al. Prevalence of hepatitis C virus infection in liver disease, renal disease and voluntary blood donors in South India. Ind J Med Microbiol 1993; 11: 291-297
11. http://www.who.int/en/ viewed on 11th January 2005.
12. O Taziki, F Espahbodi. Prevalence of Hepatitis C Virus Infection in Haemodialysis Patients. Saudi journal of kidney diseases and transplantation 2008;19(3):475-478
