A Clinical Profile of Oral Submucous Fibrosis
A Clinical Profile of Oral Submucous Fibrosis
Keywords:
Areca nut, clinical staging, histopathological grading, oral submucous fibrosisAbstract
Assistance Professoer, B. J. Medical College, Ahmedabad, ****Assistance Professor, Govt.Medical College, Bhavnagar
Abstracts: Background: Oral submucous fibrosis (OSF) is a precancerous condition associated with the use of areca nut in various forms. There are very few reports to correlate the clinical stage to histopathological grading in OSF. Materials and Methods: A hospital-based study was conducted on 80 oral Submucous Fibrosis cases who visited our hospital in Jamnagar.. A detailed history of each patient was recorded along with a clinical examination. Biopsy was performed for histopathological correlation. Clinical stage of the disease in terms of the ability to open one's mouth was correlated with histopathological grading. Results: The male to female ratio of OSF cases was 3:1. All forms of areca nut products were associated with OSF. Chewing of paanmasala was associated with early presentation of OSF as compared to chewing of the betel nut The the result of all conservative therapy fails to reverse the disease. Conclusion: result of study recommend primary prevention for prevention of OSF
References
2. Pindborg J, Sirsat S. Oral submucous fibrosis. Oral Surgery, Oral Medicine, And Oral Pathology 1966;22(6):764.
3. Rajendran R. Oral submucous fibrosis: etiology, pathogenesis, and future research. Bulletin of the World Health Organization1994;72(6):985-96.
4. Phatak A. Fibrin producing factor in Oral Sub-Mucous Fibrosis. Indian Journal of Otolaryngology and Head & Neck Surgery 1979; 31(4):103-4.
5. Rajendran R, Sugathan C, Remani P, Ankathil R, Vijayakumar T. Cell mediated and humoral immune responses in oral submucous fibrosis. Cancer1986;58(12):2628-31.
6. Canniff J, Harvey W, Harris M. Oral submucous fibrosis: its pathogenesis and management. British Dental Journal1986;160(12):429-34.
7. Sinor P, Gupta P, Murti P, Bhonsle R, Daftary D, Mehta F, Pindborg J. A case control study of oral submucous fibrosis with special reference to the etiologic role of areca nut. Journal of Oral Pathology & Medicine1990;19(2):94-8.
8. Murthi PR, Bhonsle RB, Gupta PC, Daftary DK, Pindborg JJ, Mehta FS. Etiology of Oral submucous fibrosis with special references to the role of areca nut chewing. J Oral Pathol Med 1995;24:145-52.
9. Murti PR, Bhonsle RB, Pindborg JJ, Daftary DK, Gupta PC, Mehta FS. Malignant transformation rate in oral submucous fibrosis over a 17-year period. Community Dent Oral Epidermol 1985;13:340-1.
10. Sinor PN, Gupta PC, Murthi PR, Bhonsle RB, Daftary DK, Mehta FS, et al. A case control study of oral sub mucous fibrosis with
special reference to the etiologic role of areca nut. J Oral Pathol Med 1990;19:94-8.
11. Neville BW, Allen CM, Damm DD, Bouquot JE. Oral and Maxillofacial pathology. WB Saunders Company: Philadelphia; 1995. p. 291.
12. Canniff JP, Harvey W, Harris M. Oral submucous fibrosis: Its pathogenesis and management. Br Dent J 1986;21:429-34.
13. Shah N, Sharma PP. Role of chewing and smoking habits in the etiology of oral submucous fibrosis: A case control study. J Oral Pathol Med 1998;28:475-9
14. Ranganathan K, Uma Devi M, Elizabeth Joshua, Arun Bhardwaj, Rooban T, Viswanathan R. Mouth opening, cheek flexibility and tongue protrusion parameters of 800 normal patients in Chennai, south India - A base line study to enable assessment of alteration in oral sub mucous fibrosis. JIDA 2001;72:78-80
15. Pindborg JJ, Bhonsle RB, Murti PR, Gupta PC, Daftary DK, Mehta FS. Incidence and early forms of oral sub mucous fibrosis. Oral Surg Oral Med Oral Pathol 1980;50:40-4.
