Histological Study of Adenomatous Goitre

Histological Study of Adenomatous Goitre

Authors

  • Dr. Vipul P Prajapati
  • Dr. Jyoti C Nayak
  • Dr. Kinnar S Desai
  • Dr. H.R. Jadav
  • Dr. H.R. Shah
  • Dr. C.A. Pensi

Keywords:

Adenomatous goiter, FNAC, Multinodular goiter, Thyroid

Abstract

Background & objectives: Multinodular goitre is probably the most common endocrine problem in the world today. Neither a well formulated nor a simple procedure is available for the management of MNG, hence the need for the present study. The aim was to study the various modes of presentation, the distribution with respect to age and sex and the usefulness of histological evaluation. Methods: This was a retrospective study of 100 cases of thyroid lesions during the period of April 2009 to October 2010. Results: Adenomatous goiter was found to be the commonest lesion with a frequency of 52 cases (52%).Most of the patients were female accounting for 90.39%. Most of the cases (53.85%) were noted in 21-40 years age group. Commonest presentation was swelling in front of the neck noted in 98% of cases. Conclusion: Commonest histological observation in the present study was adenomatous goitre in 52%. Majority of the patients were females with a M:F ratio of 1:9.4, with the commonest age group being 31-40 yrs. Almost all patients presented with swelling in front of the neck, with other complaints being that of pain, discomfort, dysphagia, dyspnoea and features of hyperthyroidism

References

1. AL – Tameem MM. The Pattern of surgically treated thyroid disease in two general hospitals in Riyadh. Saudi Med J 1987; 8: 61–6.
2. Jameson JL, Weetman AP. Disease of the Thyroid Gland ch 320 in Harrison’s Principles of Internal Medicine, vol 2, 16t h ed, New york: Mc Graw Hill, 2005. Pp 2106-2117.
3. Mishra A, Agarwal A, Agarwal G, Mishra SK. Total thyroidectomy for benign thyroid disorders in an endemic region. World J Surg 2001; 25: 307–310.
4. Franklyn JA. The management of hyperthyroidism. N Engl J Med 1994; 330: 1731 1738.
5. John B. Hanks. Thyroid Chapter 32, Sabiston Textbook of Surgery, 16th edition. Townsent Jr. et al. Harcourt Asia Pvt. Ltd, India 2001, pp 603-628.
6. Salman Yousuf Guraya, Omer Al Faroug Eltinay: Total Thyroidectomy for Bilateral Benign Thyroid Disease: Safety Profile and Therapeutic Efficacy. Kuwait Medical Journal 2007; 39 (2): pages 149-152.
7. Martin. A Nzegwu et al: A Histological Update of Thyroid Lesions in Enugu, Nigeria: A 5- Year Retrospective Study. Asian J. Exp. Biol. Sci., Vol 1 (2) 2010; pages 430 – 433.
8. Nazar Hussain et al: Pattern of surgically treated thyroid disease in Karachi: Biomedica Vol. 21, Jan. – Jun, 2005.
9. L. P. Bron and C. J. O’Brien: Total thyroidectomy for clinically benign disease of the thyroid gland. British Journal of Surgery 2004; 91: pages 569–574.
10. Das S. The thyroid and parathyroid in A consice textbook of surgery, 3rd ed, calcutta, 2004, pp642-676.
11. Ahuja: Profile of nodular goitre. J Assoc Phy Ind 1968; 16: pages 699-707.
12. Kapoor M M: Solitary thyroid nodule. Ind J Surg, 1982; 12: pages 166-168.
13. Tan GH, Gharib H. Thyroid incidentalomas: management approaches to non palpable nodules discovered incidentally on thyroid imaging. Ann Intern Med 1997;126:226-31.
14. Nygaard B, Hegedus L, Gervil M, et al: "Radioiodine treatment of multinodular non-toxic goitre". Br Med J 1993; pages 828-832.
15. Rehman A.U et al: Histopathological Evaluation of 432 Cases of Goiter. Annals Vol No. 2 APR. – JUN; 2009.
16. Antonio, Alfonso, George S M, Chrisoudias M. Tracheal or oesophageal compression due to benign thyroid disorders. Am J Surg 1981; 142: pages 350- 354.
17. Schlesinger, M. J., Gargill, S. L. and Saxe, I. M. (1938). Studies in Nodular Goitre. Journal of the American Medical Association, 110, 1638.

Downloads

Published

2012-06-30

How to Cite

Prajapati, D. V. P., Nayak, D. J. C., Desai, D. K. S., Jadav, D. H., Shah, D. H., & Pensi, D. C. (2012). Histological Study of Adenomatous Goitre: Histological Study of Adenomatous Goitre. National Journal of Integrated Research in Medicine, 3(2), 59–62. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/1996

Issue

Section

Original Articles

Most read articles by the same author(s)