Prevalence of Uropathogens In Various Age Groups & Their Resistance Pattern In A Tertiary Care Hospital In Central India
Prevalence of Uropathogens
DOI:
https://doi.org/10.70284/njirm.v2i4.1930Keywords:
Urinary Tract Infection(UTI), Uropathogens, ASTAbstract
Background: The prevalence of multidrug resistance among uropathogens in rapidly increasing. Analysis of the prevalence in various age groups and the common antimicrobial co-resistance pattern of uropathogens isolated from patients in a tertiary care hospital would have important implication for patient care. Methods: A total of 1383 urine samples received during year 2010 were processed. Urine microscopy & culture was done using standard microbiological techniques. Organisms were identified by standard microbiological techniques. Antimicrobial susceptibility testing was done as per CLSI guidelines.Results: A total of 426 uropathogens were isolated. E coli were seen in 65.96 % (most common) followed by Klebsiella spp. 12.44%. Enterococcus was the commonest Gram positive isolate (5.86%). Urinary tract infection (UTI) was seen in 59.86% females as compared to 40.14% males. Average antimicrobial resistance for E.coli 75.74%, Klebsiella spp. 47.45%, Proteus 65.54%, Pseudomonas 75.89%, Enterococci 66.54%, Staphylococcus aureus 39.28%, Staphylococcus saprophyticus 47.79%.
References
2. Bajaj JK, Karyakarte RP, Kulkarni JD, Deshmukh AB. Changing aetiology of urinary tract infections and emergence of drug resistance as a major problem.J Commun Dis.1999 Sep;31(3):181-4.
3. El-Mahmood Abubakar Antimicrobial susceptibility pattern of pathogenic bacteria causing urinary tract infections -Journal of Clinical Medicine and Research Vol. 1(1) pp. 001-008, October, 2009. http://www.academicjournals.org/JCMR
4. Kass EH. Asymptomatic infections of the urinary tract. Trans Assoc Am Physicians. 1956, 69:56-64.
5. National Committee for Clinical Lab Standards, Performance Standardization for Antimicrobial Disc Susceptibility test. 4th ed. Villanona PA. NCC 1993; DC M2 AS.
6. Azra S. Hasan, D. Nair, J Kaur, G. Baweja, M Deb, P. Aggarwal, Resistance patterns of urinary isolates in a Tertiary Indian Hospital.
7. Olafsson M, Kristinsson KG. Sigurdsson JA. Urinary tract infections, antibiotic resistance and sales of antimicrobial drugs--an observational study of uncomplicated urinary tract infections in Icelandic women. Scand J Prim Heal Care. 2000; 18(1):35-8.
8. Gupta K, Scholes D, Stamm WE. Increasing prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in women. JAMA.1999; 281(8):736-8.
9. Anderson JE. Seasonality of symptomatic bacterial urinary infections in women. J Epidemiol Community Health. 1983; 37(4): 286-90.
10. Ram S, Gupta R, Gaheer M. Emerging antibiotic resistance among the uropathogens. Indian J Med Sci 2000; 54(9):388-94.
11. Mathai E, Grape M, Kronvall G. Integrons and multidrug resistance among Escherichia coli causing Community-acquired urinary tract infection in southern India. APMIS. 2004; 112(3):159-64.
12. Farrell DJ, Morrissey I, De Rubeis D, Robbins M, Felmingham D. A UK multicentre study of the antimicrobial susceptibility of bacterial
pathogens causing urinary tract infection. J Infect. 2003; 46(2):94-100.
13. Huovinen P, Cars O. Control of antimicrobial resistance: time for action. The essentials of control already well known. BMJ. 1998; 317(7159):613-4
