Relationship between Smoking and Pulmonary Functions
Relationship Between Smoking And Pulmonary Functions
DOI:
https://doi.org/10.70284/njirm.v2i4.1929Keywords:
Smoking, Pulmonary function tests (PFTs), Lung volumes and capacities, Chronic obstructive pulmonary diseases (COPD)Abstract
Background: Smoking is the most important factor contributing to the development of chronic
obstructive pulmonary disease and is one of the major health risks in modern times. Aim: The purpose of the
present study was to determine the relationship between cigarette smoking and pulmonary function tests
between various groups of smokers and non-smokers. Methods: The study was carried out in 100 male
subjects between 19-52 years of age. The subjects were drawn from the community such that they could be
grouped as non-smokers (25), mild smokers (25), moderate smokers (25), and chronic smokers (25) according
to their questionnaire response. Pulmonary Function Tests were carried out in each subject with a
computerized spirometer. The various data was collected, compiled, statistically analyzed and valid
conclusions were drawn Results: Results indicate that smoking is generally associated with lower levels of
pulmonary functions. . It was established that pulmonary functions decreased with increasing number of pack
years. The negative association was evident in most lung functions and capacities, but was largest and most
progressive in FEV1, FEV1/FVC, FEF25-75% and PEFR. Conclusion: Pulmonary function data in smokers indicate
narrowing of smaller airways, chiefly bronchioles. Rapidly declining pulmonary functions in smokers with
increasing number of pack years is predictive of increased risk of development of chronic obstructive
pulmonary disease (COPD). The study observed that spirometry was an effective and easy method for
detection of COPD in risk group population like smokers and thus promotes smoking cessation efforts to
reduce the burden of COPD in the community
References
volume characteristics of the lung. Indian Journal
of Physiol Pharmacol, 1992; 36(3):169-173.
2. Datey K K and Dalvi C P. Tobacco and Health.
Indian Journal of Chest Diseases1972; 14-158-
167.
3. Bhinde S V, Jayant Kand Pakhale S S. Chemical
analysis of smoke of Indian Cigarettes, bidis and
other indigenous forms of smoking levels of
steam-volatile phenol, hydrogen cyanide and
benzopyrene. Indian Journal of Chest Diseases
and Allied Sciences 1990; 32(2):75-81.
4. WalterS and Boyapati J. Longitudnal study of
lung function development in a cohort of Indian
medical students: Interaction of respiratory
allergy and smoking. Indian Journal Physiol
Pharmacol 1991; 35(1):44-48.
5. Parks G, Greenhalgh T, Giffin M, and Dent R.
Effect of smoking quit rate of telling patients
their lung age: the step 2 qui randomized control
trial. BMJ 2008, 336:598.
6. Mosharraf-Hossain KM, Islam S, Kalam Azzad A,
Pasha MM, Sultana F, Hossain RZ, Amin A,
Murshed KM. Detection of Chronic Obstructive
Pulmonary disease using spirometric screening.
Mymensingh Med J. 2009 Jan; 18 (suppl): S 108-
112.
7. DuBois D and DuBois E. Clinical calorimeter: A
formula to estimate the approximate surface if
height and weight be known. Arch. Inter. Med.,
1961; 17: 863-871.
8. Cotes JE. Lung Function Assessment and
Application in Medicine. Blackwell Sci
Publ,Oxford, 1965;345.
9. Rai UC and Nancy NC. Effect of snuff on
pulmonary function tests. Ind Journ of Chest Dis
and All Sci, 1980; 22:147-151.
10. Dhand R and Malik SK. Long term effects of
tobacco smoking results of a spirometric study in
300 old men. Ind Jour Chest Dis and All Sci, 1985;
27(1):44-49.
11. Nag S and Dey SK. Spirometric standard for nonsmokers
and smokers of India (Eastern Region).
Japanese Jour of Physiology, 1988; 38:283-298.
12. Sherril DL, Lebowitz MD, Knudson RJ, Burrows B.
Longitudnal methods for describing the
relationship. Eur Respir J 1993 Marc; 6(3):342-8.
13. Chhabra SK, Rajpal S, Gupta R. Patterns of
smoking in Delhi and Comparison of chronic
respiratory morbidity among beedi and cigarette
smokers. Ind J Chest Dis Allied Sci 2001 Jan-Mar,
43(1):19-26.
14. Nancy NR and Rai UC. Study of forced expiratory
spirogram in South Indian beedi smokers and
cigarette smokers. Ind J Chest Dis and Alli Sci,
1983; 25:25-30.
15. Unverdorben M, Mostert A, Munjal S, Vander Bill
A, Potgreter L, Venter C, Liang Q, Meyer B,
Roething HJ. Acute effects of cigarette smoking
on pulmonary functions. Reqil Toxicol Pharmacol
2010 Jul-Aug; 57(2-3):241-6.
16. Siatkowska H, Jastrzebski D, Kozielski J. Smoking
and clinical manifestations, lung function
impairement resulting comorbidities. Pol Merkur
Lekarski. 2010 July; 29(169):8-13.
17. Islam SS, Schottenfeld D. Declining FEV1 and
chronic productive cough in cigarette smokers: a
25 year prospective study of lung cancer
incidence in Tecumseh, Michigan. Cancer
Epidermal Biomarkers Prev 1994 Jan; 3(4):289-
298.
18. Walter S, Nancy NR, CR Collier. Changes in the
forced expiratory spirogram in young male
smokers. American Review of Respiratory Dis,
1979; 119:79-82.
19. Marcq M and Minette A. Lung function changes
in smokers with normal conventional spirometry.
Am Rev Respir Dis. 1976; 114:723-38.
20. Beck GJ, Doyle CA, Schachter EN. Smoking and
Lung Function.Am Rev Respir Dis
1981:123(2):149-155.
