Seroprevalence and Trends of HIV, HBV, HCV and Syphilis Markers Among Blood Donors In Western Vidarbha Region
Seroprevalence and Trends of HIV, HBV, HCV and Syphilis Markers Among Blood Donors
Keywords:
Seroprevalence, Blood donors, Transfusion transmissible infections (TTIs) and Enzyme linked Immunosorbent assay (ELISA)Abstract
Background: Transfusion transmissible diseases continue to be a threat to safe transfusion practices. We analyzed the prevalence and trends of HIV, HBV, HCV and Syphilis markers among voluntary and replacement blood donors in a 6 years retrospective study from January 2010 till December 2015 at the blood bank Government Medical College and Hospital Akola, Maharashtra. Aims & objectives: To access the seroprevalence and trends of HIV, HBV, HCV and Syphilis markers among blood donors and access the level of blood safety. Methods: A total of 36781 healthy blood donations were screened for Anti-HIV IgG and IgM antibodies (ELISA method using fourth generation Microlisa HIV Ab detection), HBsAg (Hepalisa Microwell ELISA),Anti- HCV IgG and IgM ( third generation HCV Microlisa Microwell ELISA ) and Rapid Card test for Treponema pallidum. Result: Out of these, 31904(86.74%) were voluntary donors and 4877 (13.26%) were replacement donors. Total 605 bags tested positive for transfusion transmissible infections. The average prevalence in percentage was found to be 1.64%. The overall seroprevalence rate of HIV, HBV, HCV and syphilis among the blood donors was 0.24%, 1.24%, 0.15% and 0.005% respectively. Conclusion: The screening of blood is the only way to prevent transfusion associated complications and this should be rigorously implemented. There is a need to stress more stringent donor selection criteria to ensure a safer blood supply. [Ajay J NJIRM 2017; 8(3):7-11]
References
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21. Zou S, Dorsey KA, Notari EP, Foster GA, Krysztof DE, Musavi F. Prevalence, incidence and residual risk of human immunodeficiency virus and hepatitis C viral infections among United States blood donors since the introduction of nucleic acid testing . Transfusion 2010;50(7):1495-1504.
22. Shrestha AC, Ghimire P, Tiwari BR, Rajkarnikar M. Transfusion transmissible infections among blood donors in Kathmandu, Nepal. J Infect Dev Ctries 2009;3(10):794-7.
23. Yanase Y, Ohida T, Kaneitha Y, Agdomag DMD, Leano PSA, Gilli CJ. The prevalene of HIV, HBV and HCV among Philippines blood donors and overseas work visa applicants. Bull World Health Prgan 2007;85(20):131-7.
24. Luksamijarulkul P, Thammata N, Tiloklur M. Seroprevalence of hepatitis B, hepatitis C, and human immunodeficiency virus among blood donors, Phitsanulok reginal Blood center, Thialand. Southeast Asian J Trop Med Public Health. 2002;33(2):272-9.
25. Buseri FI, Muhibi MA, Jeremiale ZA. Seo epidemilogy of transfusion-transmmisible infectionsious diseases among blood donors in Osoglor,south-west Nigeria. Blood Transfus 2009;7:293-9.
2. Lgbida F, Muhibi MA, Jeremiah ZA. Sero-epidemiology of transfusion-transmissible infectious diseases among blood donors in Osogbo, south-west Nigeria. Blood Transfus 2009;7(4):293-9.
3. Kulkarni N. Analysis of the seroprevalence of HIV, HBsAg, HCV and syphilitic infections detected in the pretransfusion blood: a short report. Int j blood transfuse immunohematol 2012;2:1-3.
4. Yadav BS, Varma AV, Singh P, Kumar R, Bandi PK. Seroprevalence of transfusion-transmitted infections (TTIs) in blood donors : a study from central India. Ind J Med Sci & Pub Health 2016;5(6):1158-61.
5. Shah M, Shah S, Gajjar M, Bhatnagar N, Soni S, Patel V. Prevalence of HIV-I/ii, HCV, HBsAg & syphilis in blood donors of Western Region in India.NJIRM 2016;7(1):12-15.
6. Lathamani K, Bhaktha G, Nayak S, Kotigadde S. Prevalence of HIV, HCV, HBV and syphilis in blood donors among the Dakshina Kannada District, India. Int J Curr Microbiol App Sci 2013;2(10):249-52.
7. Drosten C, Nippraschk T, Manegold C, Meisel H, Brixner V, Roth WK, Apedjinov a, Gunther S. Prevalence of hepatitis B virus DNA in antiHBC positive/HBsAg- negative sera correrates with HCV but not HIV serostatus. J ClinVirol.2004;29:59-68.
8. Filayson MDC, Hayes PC, Simpson KJ. In: Davidson’s principles and practice of medicine. Haslett C, Chilvers ER, Hunters JAA,editor. Churchill Living Stone, London; 1999. Diseases of the liver and biliary system: Hepatitis;pp 706-715.
9. Nada HA, Atwa M. Seroprevalence of HBV, HCV, HIV and syphilis markers among blood donors at Suez Canal University hospital blood bank. J Blood Disorders Transf2013;5(1):117
10. Khamankar ST, Hiwale KM,Bhagat VM, Bhake AS. Seroprevalence of transfusion transmitted infection and utility of blood units in a tertiary care hospital in central India. Ind J of basic & app med res dec 2014; vol4 (1): 7-13.
11. Bembde AS, Mahajan NA, BhaleCP. Prevalence of transfusion transmitted viral diseases among blood donors in MGM medical College, Aurangabad, Maharashtra. Int J Health Sci Res.2013;3(1):26-32.
12. Arora D, Arora B, Khetarpal A. Seroprevalence of HIV, HBV, HCV and syphilis in blood donors in Southern Haryana. Indian J Pathol Microbiol 2010;53:308-309.
13. Singh B, Verma M, Kotru M, Verma K, Batra M. Prevalance of HIV and VDRL seropositivity in blood donors in Delhi. Ind J Med Res 2005;122:234-6.14. Pahuja S, Sharma M, Baitha B, Jain M. Prevalence and trends of markers of hepatitis C virus, hepatitis B virus and human immunodeficiency virus in elhi blood donors, a hospital based study. Jpn J Inf Dis 2007;60:389-91.
15. Singh K, Bhat S, Shastry S. Trends in seroprevalence of Hepatitis B virus infection among blood donors of costal Karnataka, India. J Infect Dev Ctries 2009;3:376-9.
16. Pallavi P, ganesh CK, Jayashree K, manjunaath GV.Seroprevalence of and trends in transfusion transmitted infections among blood donors in auniversity hospital blood bank: a 5 year study. Ind J Hematol Blood Transfus.2011;27(1):1-6.
17. Patel S, Popat C, Muzumdar V, Shah M, Shringpure K, Mehta KG.Sero Prevalence of HIV, HCV, HBV and syphilis in blood donors at a tertiary hospital (blood bank) in Vadodara. Int J Med Sci & Pub Health2013;2(3):747-750
18. Das BK, Gayen BK, Aditya S, Chakrovorty SK, Datta PK, Joseph A. Seroprevalence of hepatitis B, hepatitis C, and human immunodeficiency virus among healthy voluntary first time blood donors in Kolkata. Ann Trop Med Public Health 2011;4(2):86-90.
19. Chaudhary V, Agrawal VK, Sexena SK, Upadhyay D, Singh A, Singh SP. Seroprevalence of common transfusion transmissible infections among blood donors in western Uttar Pradesh, India. Int J Med Sci Public Health.2014;3(11):1381-4.
20. Bommanahalli B, Javali R, Gonda K, Siddartha K, Shashikala KP. Seroprevalence of hepatitis B, hepatitis C viral infections among blood donors of central Karnataka, India. Int J Med Sci Public Health.2014;3(1):272-5.
21. Zou S, Dorsey KA, Notari EP, Foster GA, Krysztof DE, Musavi F. Prevalence, incidence and residual risk of human immunodeficiency virus and hepatitis C viral infections among United States blood donors since the introduction of nucleic acid testing . Transfusion 2010;50(7):1495-1504.
22. Shrestha AC, Ghimire P, Tiwari BR, Rajkarnikar M. Transfusion transmissible infections among blood donors in Kathmandu, Nepal. J Infect Dev Ctries 2009;3(10):794-7.
23. Yanase Y, Ohida T, Kaneitha Y, Agdomag DMD, Leano PSA, Gilli CJ. The prevalene of HIV, HBV and HCV among Philippines blood donors and overseas work visa applicants. Bull World Health Prgan 2007;85(20):131-7.
24. Luksamijarulkul P, Thammata N, Tiloklur M. Seroprevalence of hepatitis B, hepatitis C, and human immunodeficiency virus among blood donors, Phitsanulok reginal Blood center, Thialand. Southeast Asian J Trop Med Public Health. 2002;33(2):272-9.
25. Buseri FI, Muhibi MA, Jeremiale ZA. Seo epidemilogy of transfusion-transmmisible infectionsious diseases among blood donors in Osoglor,south-west Nigeria. Blood Transfus 2009;7:293-9.
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Published
2018-02-02
How to Cite
Jungare, A., Patil, S., Sarate, D., & Jungare, S. (2018). Seroprevalence and Trends of HIV, HBV, HCV and Syphilis Markers Among Blood Donors In Western Vidarbha Region: Seroprevalence and Trends of HIV, HBV, HCV and Syphilis Markers Among Blood Donors. National Journal of Integrated Research in Medicine, 8(3), 7–11. Retrieved from http://nicpd.ac.in/ojs-/index.php/njirm/article/view/1235
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