Study of Minor and Major adverse drug reaction of intravenous Iron Sucrose in the treatment of severe iron deficiency anemia.

Abstract

Anaemia is a major health problem worldwide. Intravenous iron sucrose appears to be treatment of choice with no
serious side effects, indicated in the rapid correction of anaemia in pregnancy or restoring maternal iron stores.
AIMS: To evaluate the effects of injectable iron sucrose therapy in terms of minor and major adverse drug
reactions in antenatal and postnatal patients. MATERIALS AND METHODOLOGY: The present study was
conducted on antenatal and postnatal patients within the age group of 19-40 years clinically diagnosed as
anaemic. Routine haematological investigations including peripheral blood smear examination, complete blood
count and injectable iron sucrose therapy was given and minor and major adverse reaction was
studied.RESULT:10 % of antenatal patient and 16% of postnatal patients developed adverse reactions to
intravenous iron sucrose. Out of 12 minor side effects 4 were developed in antenatal patients and 8 in postnatal
patients. Only 1 major reaction developed in antenatal and no major reaction developed in postnatal patient.
CONCLUSION: Intravenous iron sucrose transfusion is an effective treatment strategy for antenatal and postnatal
patients with negligible side effect and leads to rapid rise in Hb level.